{"id":48,"date":"2026-04-06T13:52:52","date_gmt":"2026-04-06T13:52:52","guid":{"rendered":"https:\/\/gesmd.es\/?page_id=48"},"modified":"2026-06-26T12:21:48","modified_gmt":"2026-06-26T12:21:48","slug":"proyecto-umbrella","status":"publish","type":"page","link":"https:\/\/gesmd.es\/?page_id=48","title":{"rendered":"UMBRELLA"},"content":{"rendered":"\n
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Proyecto UMBRELLA<\/h2><\/div>\n\n\n\n

En la \u00faltima d\u00e9cada, los avances en la secuenciaci\u00f3n de nueva generaci\u00f3n (NGS) han permitido la integraci\u00f3n de la gen\u00e9tica molecular en el diagn\u00f3stico y en algoritmos de estratificaci\u00f3n pron\u00f3stica de los SMD. A pesar de ello, los SMD siguen siendo un reto: su diagn\u00f3stico y pron\u00f3stico son complejos y las opciones terap\u00e9uticas, limitadas. Esto gener\u00f3 una necesidad clara: mejorar el manejo cl\u00ednico y avanzar hacia una medicina personalizada para estos pacientes.<\/strong><\/p>\n<\/div>\n\n\n\n

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\"Umbrella<\/figure><\/div>\n<\/div>\n<\/div><\/div>\n\n\n\n
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La historia de UMBRELLA y su evoluci\u00f3n<\/h2><\/div>\n<\/div><\/div>\n\n\n\n
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En 2021 surge UMBRELLA<\/strong>, un proyecto coordinado de cuatro centros espa\u00f1oles, financiado por el Instituto de Investigaci\u00f3n Carlos III y liderado desde el Hospital Universitario de Salamanca\/ Instituto de investigaci\u00f3n biom\u00e9dica de Salamanca. UMBRELLA nace en el seno del GESMD, cuyo objetivo es promover la investigaci\u00f3n, fomentar la participaci\u00f3n en el RESMD y buscar soluciones integrales a la enfermedad.<\/p>\n<\/div>\n\n\n\n

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Finalizado<\/p>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n

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\"\"<\/figure><\/div>\n\n\n\n

En 2024, UMBRELLA evoluciona hacia UMBRELLA SUMMA<\/strong>. Sus objetivos generales incluyen evaluar nuevas t\u00e9cnicas diagn\u00f3sticas como el Mapeo \u00d3ptico del Genoma, realizar secuenciaci\u00f3n gen\u00e9tica avanzada para la mejora del pron\u00f3stico de los SMD en Espa\u00f1a y crear un biobanco para futuras investigaciones. Adem\u00e1s, incorpora subproyectos dirigidos a la investigaci\u00f3n de diferentes aspectos y subgrupos de SMD.<\/p>\n<\/div>\n\n\n\n

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M\u00e1s informaci\u00f3n<\/div><\/path><\/svg><\/span><\/a><\/div><\/div>\n<\/div><\/div>\n<\/div>\n\n\n\n
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\"\"<\/figure><\/div>\n\n\n\n

En 2025, surge UMBRELLA SUMMA Legacy<\/strong>, consolidando los proyectos anteriores y ampliando la colaboraci\u00f3n a 25 instituciones, con un presupuesto superior a 3 millones de euros. Adem\u00e1s de compartir algunos de los objetivos con UMBRELLA SUMMA, este proyecto pretende integrar datos cl\u00ednicos, gen\u00e9ticos y moleculares e incluir la perspectiva del paciente en el RESMD, validar nuevas metodolog\u00edas diagn\u00f3sticas y estudiar casos de SMD complejos. UMBRELLA SUMMA Legacy tambi\u00e9n busca desarrollar herramientas de IA para mejorar el diagn\u00f3stico, pron\u00f3stico y tratamiento personalizado y promover la formaci\u00f3n, difusi\u00f3n y colaboraci\u00f3n entre profesionales del GESMD. Desde el inicio, la iniciativa ha ido incorporando tecnolog\u00edas y propuestas nuevas para ampliar y enriquecer la idea inicial de UMBRELLA.<\/p>\n<\/div>\n\n\n\n

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M\u00e1s informaci\u00f3n<\/div><\/path><\/svg><\/span><\/a><\/div><\/div>\n<\/div><\/div>\n<\/div>\n<\/div><\/div>\n\n\n\n
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\u00bfC\u00f3mo puedo participar en UMBRELLA?<\/h2><\/div>\n\n\n\n
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1. ENV\u00cdO DE MUESTRAS PARA INVESTIGACI\u00d3N<\/div><\/path><\/svg><\/span><\/a><\/div><\/div>\n<\/div><\/div>\n\n\n\n
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2. ENV\u00cdO DE MUESTRAS PARA SECUENCIACI\u00d3N MASIVA<\/div><\/path><\/svg><\/span><\/a><\/div><\/div>\n<\/div><\/div>\n\n\n\n
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3. ENV\u00cdO DE MUESTRAS PARA MAPEO \u00d3PTICO DEL GENOMA (OGM<\/div><\/path><\/svg><\/span><\/a><\/div><\/div>\n<\/div><\/div>\n<\/div>\n\n\n<\/div><\/div>\n\n\n\n

<\/p>\n","protected":false},"excerpt":{"rendered":"

Proyecto UMBRELLA En la \u00faltima d\u00e9cada, los avances en la secuenciaci\u00f3n de nueva generaci\u00f3n (NGS) han permitido la integraci\u00f3n de […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_uag_custom_page_level_css":"","site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"disabled","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"class_list":["post-48","page","type-page","status-publish","hentry"],"uagb_featured_image_src":{"full":false,"thumbnail":false,"medium":false,"medium_large":false,"large":false,"1536x1536":false,"2048x2048":false},"uagb_author_info":{"display_name":"gesmd.jc.alvarez@ene.es","author_link":"https:\/\/gesmd.es\/?author=1"},"uagb_comment_info":0,"uagb_excerpt":"Proyecto UMBRELLA En la \u00faltima d\u00e9cada, los avances en la secuenciaci\u00f3n de nueva generaci\u00f3n (NGS) han permitido la integraci\u00f3n de […]","_links":{"self":[{"href":"https:\/\/gesmd.es\/index.php?rest_route=\/wp\/v2\/pages\/48","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/gesmd.es\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/gesmd.es\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/gesmd.es\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/gesmd.es\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=48"}],"version-history":[{"count":121,"href":"https:\/\/gesmd.es\/index.php?rest_route=\/wp\/v2\/pages\/48\/revisions"}],"predecessor-version":[{"id":3582,"href":"https:\/\/gesmd.es\/index.php?rest_route=\/wp\/v2\/pages\/48\/revisions\/3582"}],"wp:attachment":[{"href":"https:\/\/gesmd.es\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=48"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}