EHA 2020:

Transcriptional regulation of Hematopoietic Stem Cells in Aging and Myelodysplastic Syndrome reveals DDIT3 as a Potential Driver of Transformation.

Teresa Ezponda1,2, Nerea Berastegui1, Juan P. Romero1,2, Marina Ainciburu1,2, Ana Alfonso2,3, Celine Philippe4, Amaia Vilas-Zornoza1,2, Patxi San Martin1,2, Laura Castro1,2, Tamara Jimenez5, Félix López5, Jesús M. Hernández5, Antonieta Molero6, Julia Montoro6, Bárbara Tazón6, Bruno Paiva2,7, Kevin Rouault-Pierre4, María Díez-Campelo5, David Valcarcel6, David Lara1,2 and Felipe Prosper2,3* –

Modelado de las patologías humanas del Síndrome Myodisplasico y Leucemia Mieloide Aguda vinculado a GATA2

Human IPSC-based model of GATA2 deficiency reveals impaired endothelial-hematopoietic development. First author: J. Castaño. Last author: A. Giorgetti.

Phase 3 Study of Lenalidomide (LEN) Vs Placebo in Non-Transfusion Dependent (TD) Low Risk Del(5q) MDS Patients – Interim Analysis of the European Sintra-REVTrial

Félix López Cadenas, MD , Eva Lumbreras , Blanca Xicoy, MD , Joaquín Sánchez, MD , Rosa Coll, MD , Bohrane Slama, MD , Jose Angel Hernandez 7* 8* 9* 10* 11* Rivas, MD, PhD , Sylvain Thepot, MD , Teresa Bernal, MD, PhD , Beatriz Arrizabalaga, MD. PhD , Agnès Guerci-Bresler, MD, PhD , Guillermo F Sanz, 12 13* 14* 15* 16* 17 18 MD, PhD , Joan Bargay, MD , Maria Luz Amigo, MD , Raquel de Paz, MD , Benet Nomdedeu, MD , Aristoteles Giagounidis , Uwe Platzbecker, MD , 19* 20 21* 22,23 24 Stefan Wickenhauser , Katharina S. Götze , Ali Arar , Jesus María Hernández Rivas, MD, PhD , Pierre Fenaux, MD, PhD , Consuelo Del Cañizo, MD, 25 26,27* PhD and Maria Diez-Campelo, MD, PhD

ASH 2020:

Results of a Clinical Trial of H3B-8800, a Splicing Modulator, in Patients with Myelodysplastic Syndromes (MDS), Acute Myeloid Leukemia (AML) or Chronic Myelomonocytic Leukemia (CMML)

David P. Steensma1, Martin Wermke2, Virginia M. Klimek3, Peter L Greenberg4, Patricia Font5, Rami S. Komrokji6, Jay Yang7, Andrew M. Brunner8, Hetty E. Carraway9, Lionel Ades10, Aref Al-Kali11, Juan Manuel Alonso Dominguez12, Ana Alonso13, Catherine C. Coombs14, H. Joachim Deeg15, William B. Donnellan16, James M. Foran17, Guillermo Garcia-Manero18, Michael B. Maris19, Malgorzata McMasters20, Jean-Baptiste Micol21, Jaime Perez De Oteyza22, Felicitas Thol23, Eunice S. Wang24, Justin M. Watts25, Silvia Buonamici26, Amy Kim26, Vikram Gourineni26, Alyssa J Marino26, Nathalie Rioux26, Joanne Schindler26, Sherri Smith26, Huilan Yao26, Xiaobin Yuan27, Kun Yu26, Uwe Platzbecker28.» ASH 2020